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European Journal of Cardio-Thoracic Surgery, Vol 11, 1067-1073, Copyright © 1997 by European Association for Cardio-thoracic Surgery
WS Peters, JA Smith, A Preovolos, M Rabinov, MR Buckland and FL Rosenfeldt
OBJECTIVE: To develop a clinically applicable method of minimally invasive
mitral valve replacement (MVR) with cardioplegia, and examine the ability
of carbon dioxide (CO2) to improve de-airing. METHODS: MVR was performed
via a 5 x 3-cm right lateral minithoracotomy in eight greyhounds.
Peripheral cardiopulmonary bypass and an ascending aortic balloon catheter
(endoaortic clamp) were used for cardioplegia and aortic root venting. The
endoaortic clamp was inflated in the ascending aorta under fluoroscopy and
cardioplegic solution was infused. In four dogs, CO2 at 2 l/min was used to
displace air in the chest. A left atriotomy was made, the valve exposed and
a mechanical valve implanted. After left atrial closure, retained
intracardiac gas was aspirated from the aortic root and collected in a
bubble-trap. The endoclamp was deflated and the animal weaned from bypass.
RESULTS: A satisfactory MVR was performed in all cases. The clamp time was
64 +/- 13 min and all dogs were stable post-bypass. In the CO2 group,
intrathoracic CO2 was maintained above 86% and 0.1 +/- 0.1 ml of gas was
collected, compared to 1.3 +/- 0.8 ml in the non-CO2 group (P < 0.05).
CONCLUSIONS: Femoro- femoral bypass and use of the endoaortic clamp allow a
safe and efficacious MVR via a right minithoracotomy in the dog. A high
intrathoracic CO2 concentration reduces the amount of retained intracardiac
gas.
ARTICLES
Mitral valve replacement via a right mini-thoracotomy in the dog: use of carbon dioxide to reduce intracardiac air
Cardiac Surgical Research Unit, Baker Medical Research Institute, Prahran VIC, Australia. 100400.2533@compuserve.com
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