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Eur J Cardiothorac Surg 2001;20:133-139
© 2001 Elsevier Science NL
a Department of Cardiothoracic Surgery, Karolinska Hospital, Stockholm, Sweden
b Department of Cardiothoracic Surgery, Trondheim University Hospital, Trondheim, Norway
c Department of Infectious Diseases, Karolinska Hospital, Stockholm, Sweden
Received 27 October 2000; received in revised form 4 April 2001; accepted 11 April 2001.
Corresponding author. Department of Cardiothoracic Surgery, St. Elisabeth Heart Centre, Trondheim University Hospital, Hans Nissens gate 3, 7018 Trondheim, Norway
e-mail: rafaelastudillo{at}hotmail.com
Objective: Using the Ley prosthesis, a 0.5 mm thick titanium alloy plate for stabilising the sternum, is a new method in the treatment of mediastinitis after open-heart surgery. We report a retrospective analysis of our experience with this device. Methods: One hundred consecutive cases of post-operative mediastinitis in the period 1992–1997 were reviewed. The primary procedure at reoperation for infection was as follows: 52 patients were treated with the Ley prosthesis and 48 patients underwent other conventional procedures. The choice of the surgical technique depended on the attending surgeon. The prosthesis was used more frequently in patients with sternal dehiscence (P<0.001) but otherwise patients' characteristics were similar in the two groups. As a control population for outcome data, 100 uninfected patients were matched with regard to operative procedure, age, sex and date of surgery. Results: The median hospital stay was 48.5 days in the mediastinitis group vs. 14 days in the control group. The all-cause 90-day mortality in the mediastinitis group was 18% vs. 5% in the control group. The 52 patients treated with the Ley prosthesis had a median length of stay in the cardiac surgery ward for 29 days vs. 41.5 days in the mediastinitis group not treated with the prosthesis (P=0.013). However, when the total length of stay including hospitals outside the cardiac surgery ward was taken into account, the prosthesis did not reduce the length of stay. Only 8/52 patients treated with the prosthesis required further surgery vs. 23/48 patients who were not primarily treated with the prosthesis (P<0.001). The Ley prosthesis had no impact on mortality. Conclusion: The Ley prosthesis is a valuable adjunct to the treatment of mediastinitis after open-heart surgery. A shorter stay at the cardiac surgery ward and a reduced need for further surgical procedures were observed when using this prosthesis.
Key Words: Heart surgery • Sternal dehiscence • Sternotomy • Mediastinitis • Hospital stay • Reoperations
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